pharma hot melt extruders
Our pharma melt extruder (PME 5) is a high quality, GMP compliant instrument for Hot Melt Extrusion (HME). The PME 5 has a standard volume of 5 ml and is engineered for user-friendliness, flexibility, speed and reliability. We also offer a set of 2 ml* barrel liners for twin-screw extrusion of a minimum amount of product (PME 2, see image below) to meet the demanding screening requirements of pharmaceutical R&D applications.
pharma hot melt extruders
Key features
Two instruments in one with 5 or 2 ml interchangeable barrel liners (other volumes on request).
Easy to fill quantitatively with water-cooled top hopper and extended, forced feeding screws, also fluffy or sticky powders.
Interchangeable, conical, fully intermeshing co-rotating screws - for optimum mixing and maximum yield.
GMP design for easy and thorough cleaning due to clamshell design and contamination-free operations.
Faster screening by cleaning screws and barrel liners in parallel during the next experiment.
Precise temperature control by seven thermocouples and six heating cartridges.
High melt torques possible (18 Nm/screw) for low-temperature extrusion and minimum degradation risk.
Dedicated software for process and rheological data.
Protocol for easy upscaling to parallel twin-screw extruders.
A compact tabletop instrument with small footprint fits in a fume hood or classified room.
Optional extras - to fully meet your specific requirements.