pharma hot melt extruders

Our pharma melt extruder (PME 5) is a high quality, GMP compliant instrument for Hot Melt Extrusion (HME). The PME 5 has a standard volume of 5 ml and is engineered for user-friendliness, flexibility, speed and reliability. We also offer a set of 2 ml* barrel liners for twin-screw extrusion of a minimum amount of product (PME 2, see image below) to meet the demanding screening requirements of pharmaceutical R&D applications.

pharma hot melt extruders

Key features

  • Two instruments in one with 5 or 2 ml interchangeable barrel liners (other volumes on request).

  • Easy to fill quantitatively with water-cooled top hopper and extended, forced feeding screws, also fluffy or sticky powders.

  • Interchangeable, conical, fully intermeshing co-rotating screws - for optimum mixing and maximum yield.

  • GMP design for easy and thorough cleaning due to clamshell design and contamination-free operations.

  • Faster screening by cleaning screws and barrel liners in parallel during the next experiment.

  • Precise temperature control by seven thermocouples and six heating cartridges.

  • High melt torques possible (18 Nm/screw) for low-temperature extrusion and minimum degradation risk.

  • Dedicated software for process and rheological data.

  • Protocol for easy upscaling to parallel twin-screw extruders.

  • A compact tabletop instrument with small footprint fits in a fume hood or classified room.

  • Optional extras - to fully meet your specific requirements.

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